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Association of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study

IMPORTANCE: Approximately 1 million patients in the United States with type 2 diabetes mellitus and mild-to-moderate kidney disease do not receive guideline-directed therapy with metformin. This may reflect uncertainty regarding the risk of acidosis in patients with chronic kidney disease. OBJECTIVE...

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Detalhes bibliográficos
Publicado no:JAMA Intern Med
Main Authors: Lazarus, Benjamin, Wu, Aozhou, Shin, Jung-Im, Sang, Yingying, Alexander, G. Caleb, Secora, Alex, Inker, Lesley A., Coresh, Josef, Chang, Alex R., Grams, Morgan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145716/
https://ncbi.nlm.nih.gov/pubmed/29868840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2018.0292
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