Prevalence of MDM2 amplification and coalterations in 523 advanced cancer patients in the MD Anderson phase 1 clinic

BACKGROUND: TP53 is the most commonly mutated gene in cancer and codes for the best studied tumor suppressor, p53. MDM2 is involved in the negative regulation of p53 and itself serves as an oncogene, reported to be overexpressed in several cancer tumor types. In this retrospective study, we assessed...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Dembla, Vikas, Somaiah, Neeta, Barata, Pedro, Hess, Kenneth, Fu, Siqing, Janku, Filip, Karp, Daniel D., Naing, Aung, Piha-Paul, Sarina Anne, Subbiah, Vivek, Tsimberidou, Apostolia M., Shaw, Kenna, Meric-Bernstam, Funda, Hong, David S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145698/
https://ncbi.nlm.nih.gov/pubmed/30237864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26075
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky