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Imaging-based clusters in current smokers of the COPD cohort associate with clinical characteristics: the SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)

BACKGROUND: Classification of COPD is usually based on the severity of airflow, which may not sensitively differentiate subpopulations. Using a multiscale imaging-based cluster analysis (MICA), we aim to identify subpopulations for current smokers with COPD. METHODS: Among the SPIROMICS subjects, we...

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發表在:Respir Res
Main Authors: Haghighi, Babak, Choi, Sanghun, Choi, Jiwoong, Hoffman, Eric A., Comellas, Alejandro P., Newell, John D., Graham Barr, R., Bleecker, Eugene, Cooper, Christopher B., Couper, David, Han, Mei Lan, Hansel, Nadia N., Kanner, Richard E., Kazerooni, Ella A., Kleerup, Eric A. C., Martinez, Fernando J., O’Neal, Wanda, Rennard, Stephen I., Woodruff, Prescott G., Lin, Ching-Long
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145340/
https://ncbi.nlm.nih.gov/pubmed/30227877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0888-7
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