Asymmetric expression of H19 and ADIPOQ in concave/convex paravertebral muscles is associated with severe adolescent idiopathic scoliosis

BACKGROUND: Adolescent idiopathic scoliosis (AIS) is the most common paediatric spinal deformity. The etiology and pathology of AIS remain unexplained, and have been reported to involve a combination of genetic and epigenetic factors. Since paravertebral muscle imbalance plays an important role in t...

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Pubblicato in:Mol Med
Autori principali: Jiang, Heng, Yang, Fu, Lin, Tao, Shao, Wei, Meng, Yichen, Ma, Jun, Wang, Ce, Gao, Rui, Zhou, Xuhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145194/
https://ncbi.nlm.nih.gov/pubmed/30241458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0049-y
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