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Metabolomics for informing adverse outcome pathways: Androgen receptor activation and the pharmaceutical spironolactone

One objective in developing adverse outcome pathways (AOPs) is to connect biological changes that are relevant to risk assessors (i.e., fecundity) to molecular and cellular-level alterations that might be detectable at earlier stages of a chemical exposure. Here, we examined biochemical responses of...

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Detalles Bibliográficos
Publicado en:Aquat Toxicol
Main Authors: Davis, JM, Ekman, DR, Skelton, DM, LaLone, CA, Ankley, GT, Cavallin, JE, Villeneuve, DL, Collette, TW
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6145081/
https://ncbi.nlm.nih.gov/pubmed/28129603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2017.01.001
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