P04.50 Doxycycline impairs mitochondrial function and protects human glioma cells from hypoxia-induced cell death: implications of using Tet-inducible systems

BACKGROUND: Inducible gene expression is an important tool in molecular biology research to study protein function. Most frequently, the antibiotic doxycycline is used for regulation of so-called tetracycline (Tet)-inducible systems. In contrast to stable gene overexpression, these systems allow inv...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Sauer, B, Luger, A, Lorenz, N I, Engel, A L, Braun, Y, Voss, M, Harter, P N, Steinbach, J P, Ronellenfitsch, M W
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Poster Presentations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144749/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.284
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