P05.46 Metachronous malignancies and brain tumor in children with germline TP53 mutation

BACKGROUND: Somatic TP53 mutations have been reported to occur in almost every type of cancer. They are common alterations in brain tumors. Nevertheless, germline mutations of TP53 gene are linked to Li-Fraumeni syndrome (LFS), a tumor susceptibility condition, characterized by an increased risk of...

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Publicat a:Neuro Oncol
Autors principals: Guidi, M, Giunti, L, Buccoliero, A, Farina, S, Fonte, C, Caporalini, C, Moscheo, C, Censullo, M, Genitori, L, Sardi, I
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Poster Presentations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144745/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.372
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