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P04.13 LRIG3 and Soluble LRIG3 Ectodomain both inhibit the Proliferation and Invasion of Glioma cells in vitro and in vivo through modulation of Met-PI3K-Akt pathway

BACKGROUND: The human leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family is a evolutionary conserved family comprising of LRIG1, 2, and 3, and encodes integral membrane proteins with an ectodomain, a transmembrane domain and a cytoplasmic tail. It is well documented that LRIG1 f...

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Publicat a:Neuro Oncol
Autors principals: Cheng, F, Mao, F, Xiao, Q, Wang, B, Guo, D
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144722/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.247
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