Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma

Monocarboxylate transporter‐4 (MCT4), a monocarboxylic acid transporter, demonstrates significantly increased expression in the majority of malignancies. We performed an experiment using BALB/C mice, and our results showed that ShMCT4 transfection or the pharmaceutic inhibition of MCT4 with 7acc1 st...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Long, Yaping, Gao, Zihe, Hu, Xiao, Xiang, Feng, Wu, Zhaozhen, Zhang, Jiahui, Han, Xiao, Yin, Liyong, Qin, Junfang, Lan, Lan, Yin, Fuzai, Wang, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143925/
https://ncbi.nlm.nih.gov/pubmed/30051648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1713
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