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Structure–Function Relationships of Glycine and GABA(A) Receptors and Their Interplay With the Scaffolding Protein Gephyrin

Glycine and γ-aminobutyric acid (GABA) are the major determinants of inhibition in the central nervous system (CNS). These neurotransmitters target glycine and GABA(A) receptors, respectively, which both belong to the Cys-loop superfamily of pentameric ligand-gated ion channels (pLGICs). Interaction...

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Veröffentlicht in:Front Mol Neurosci
Hauptverfasser: Kasaragod, Vikram B., Schindelin, Hermann
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143783/
https://ncbi.nlm.nih.gov/pubmed/30258351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00317
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