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Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease

Entamoeba histolytica is the etiologic agent of amebic dysentery, though clinical manifestation of infection is highly variable ranging from subclinical colonization to invasive disease. We hypothesize that host genetics contribute to the variable outcomes of E. histolytica infection; thus, we condu...

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Veröffentlicht in:mBio
Hauptverfasser: Wojcik, Genevieve L., Marie, Chelsea, Abhyankar, Mayuresh M., Yoshida, Nobuya, Watanabe, Koji, Mentzer, Alexander J., Carstensen, Tommy, Mychaleckyj, Josyf, Kirkpatrick, Beth D., Rich, Stephen S., Concannon, Patrick, Haque, Rashidul, Tsokos, George C., Petri, William A., Duggal, Priya
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143743/
https://ncbi.nlm.nih.gov/pubmed/30228239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01668-18
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