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Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

Glioblastoma (GBM) is the deadliest type of brain tumor, and glioma stem cells (GSCs) contribute to tumor recurrence and therapeutic resistance. Thus, an oncolytic virus targeting GSCs may be useful for improving GBM treatment. Because Zika virus (ZIKV) has an oncolytic tropism for infecting GSCs, w...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Chen, Qi, Wu, Jin, Ye, Qing, Ma, Feng, Zhu, Qian, Wu, Yan, Shan, Chao, Xie, Xuping, Li, Dapei, Zhan, Xiaoyan, Li, Chunfeng, Li, Xiao-Feng, Qin, Xiaoling, Zhao, Tongyang, Wu, Haitao, Shi, Pei-Yong, Man, Jianghong, Qin, Cheng-Feng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143740/
https://ncbi.nlm.nih.gov/pubmed/30228241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01683-18
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