Inhibition of Rho Activity Increases Expression of SaeRS-Dependent Virulence Factor Genes in Staphylococcus aureus, Showing a Link between Transcription Termination, Antibiotic Action, and Virulence

Staphylococcus aureus causes various diseases ranging from skin and soft tissue infections to life-threatening infections. Adaptation to the different host niches is controlled by a complex network of transcriptional regulators. Global profiling of condition-dependent transcription revealed adaptati...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Nagel, Anna, Michalik, Stephan, Debarbouille, Michel, Hertlein, Tobias, Gesell Salazar, Manuela, Rath, Hermann, Msadek, Tarek, Ohlsen, Knut, van Dijl, Jan Maarten, Völker, Uwe, Mäder, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143737/
https://ncbi.nlm.nih.gov/pubmed/30228237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01332-18
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