Diabetes Modulates MicroRNAs 29b-3p, 29c-3p, 199a-5p and 532-3p Expression in Muscle: Possible Role in GLUT4 and HK2 Repression

The reduced expression of solute carrier family 2, facilitated glucose transporter member 4 (GLUT4) and hexokinase-2 (HK2) in skeletal muscle participates in insulin resistance of diabetes mellitus (DM). MicroRNAs (miRNAs) have emerged as important modulators of mRNA/protein expression, but their ro...

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Pubblicato in:Front Endocrinol (Lausanne)
Autori principali: Esteves, João V., Yonamine, Caio Y., Pinto-Junior, Danilo C., Gerlinger-Romero, Frederico, Enguita, Francisco J., Machado, Ubiratan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Endocrinology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143689/
https://ncbi.nlm.nih.gov/pubmed/30258406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00536
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