TMCO1 is essential for ovarian follicle development by regulating ER Ca(2+) store of granulosa cells

TMCO1 (transmembrane and coiled-coil domains 1) is an endoplasmic reticulum (ER) transmembrane protein that actively prevents Ca(2+) stores from overfilling. To characterize its physiological function(s), we generated Tmco1(−/−) knockout (KO) mice. In addition to the main clinical features of human...

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Pubblicato in:Cell Death Differ
Autori principali: Sun, Zhongshuai, Zhang, Hui, Wang, Xi, Wang, Qiao-Chu, Zhang, Chuanchao, Wang, Jiu-Qiang, Wang, Yi-Han, An, Chao-Qiang, Yang, Ke-Yan, Wang, Yun, Gao, Fei, Guo, Caixia, Tang, Tie-Shan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143536/
https://ncbi.nlm.nih.gov/pubmed/29467381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0067-x
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