Dysregulated calcium homeostasis in cystic fibrosis neutrophils leads to deficient antimicrobial responses

Cystic fibrosis (CF), one of the most common human genetic diseases worldwide, is caused by a defect in the CF transmembrane conductance regulator (CFTR). Patients with CF are highly susceptible to infections caused by opportunistic pathogens including Burkholderia cenocepacia, which induce excessiv...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Robledo-Avila, Frank H, Ruiz-Rosado, Juan de Dios, Brockman, Kenneth L, Kopp, Benjamin T, Amer, Amal O, McCoy, Karen, Bakaletz, Lauren O, Partida-Sanchez, Santiago
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143431/
https://ncbi.nlm.nih.gov/pubmed/30120123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800076
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