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Direct visualization of a native Wnt in vivo reveals that a long-range Wnt gradient forms by extracellular dispersal

Wnts are evolutionarily conserved signaling proteins with essential roles in development and disease that have often been thought to spread between cells and signal at a distance. However, recent studies have challenged this model, and whether long-distance extracellular Wnt dispersal occurs and is...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Pani, Ariel M, Goldstein, Bob
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143344/
https://ncbi.nlm.nih.gov/pubmed/30106379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38325
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