Efficacy of tyrosine kinase inhibitors (TKIs) as third-line therapy in patients with chronic myeloid leukemia in chronic phase who have failed 2 prior lines of TKI therapy

We analyzed a cohort of 26 patients with chronic myeloid leukemia who had failed imatinib and a second tyrosine kinase inhibitor but were still in first chronic phase and identified prognostic factors for response and outcomes. The achievement of a prior cytogenetic response on imatinib or on second...

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Veröffentlicht in:Blood
Hauptverfasser: Ibrahim, Amr R., Paliompeis, Christos, Bua, Marco, Milojkovic, Dragana, Szydlo, Richard, Khorashad, Jamshid S., Foroni, Letizia, Reid, Alistair, de Lavallade, Hugues, Rezvani, Katayoun, Dazzi, Francesco, Apperley, Jane F., Goldman, John M., Marin, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Clinical Trials and Observations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143154/
https://ncbi.nlm.nih.gov/pubmed/20833982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-291922
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