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The Methanosarcina mazei MM2060 gene encodes a bifunctional kinase/decarboxylase enzyme involved in cobamide biosynthesis

Cobamides (Cbas) are synthesized by many archaea, but some aspects of Cba biosynthesis in these microorganisms remain unclear. Here, we demonstrate here that the ORF MM2060 in the archaeum Methanosarcina mazei strain Gö1 encodes a bifunctional enzyme with L-threonine-O-3-phosphate (L-Thr-P) decarbox...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Tavares, Norbert K., Zayas, Carmen L., Escalante-Semerena, Jorge C.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6143143/
https://ncbi.nlm.nih.gov/pubmed/29950091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00546
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