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Assessment of Off-label Prescribing Compared With FDA-Approved Treatment With Combined Dextromethorphan and Quinidine in 2 Commercial Insurance Databases

IMPORTANCE: In 2010, the US Food and Drug Administration approved a combination of dextromethorphan hydrobromide and quinidine sulfate with an Orphan Drug Act designation for the treatment of pseudobulbar affect in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS). This me...

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Detalhes bibliográficos
Publicado no:JAMA Intern Med
Main Authors: Fralick, Michael, Sacks, Chana A., Kesselheim, Aaron S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142962/
https://ncbi.nlm.nih.gov/pubmed/30039158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2018.3016
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