Effect of Oral Valproic Acid vs Placebo for Vision Loss in Patients With Autosomal Dominant Retinitis Pigmentosa: A Randomized Phase 2 Multicenter Placebo-Controlled Clinical Trial

IMPORTANCE: There are no approved drug treatments for autosomal dominant retinitis pigmentosa, a relentlessly progressive cause of adult and childhood blindness. OBJECTIVES: To evaluate the potential efficacy and assess the safety of orally administered valproic acid (VPA) in the treatment of autoso...

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Xehetasun bibliografikoak
Argitaratua izan da:JAMA Ophthalmol
Egile Nagusiak: Birch, David G., Bernstein, Paul S., Iannacone, Alessandro, Pennesi, Mark E., Lam, Byron L., Heckenlively, John, Csaky, Karl, Hartnett, Mary Elizabeth, Winthrop, Kevin L., Jayasundera, Thiran, Hughbanks-Wheaton, Dianna K., Warner, Judith, Yang, Paul, Fish, Gary Edd, Teske, Michael P., Sklaver, Neal L., Erker, Laura, Chegarnov, Elvira, Smith, Travis, Wahle, Aimee, VanVeldhuisen, Paul C., McCormack, Jennifer, Lindblad, Robert, Bramer, Steven, Rose, Stephen, Zilliox, Patricia, Francis, Peter J., Weleber, Richard G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Medical Association 2018
Gaiak:
Original Investigation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142953/
https://ncbi.nlm.nih.gov/pubmed/29879277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaophthalmol.2018.1171
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