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New therapeutic targets in transfusion-dependent and -independent thalassemia

β-Thalassemias are characterized by reduced production of β-globin chain, resulting in α/β-chain unbalance and precipitation of α-globin–heme complexes and determining ineffective erythropoiesis. Ineffective erythropoiesis, chronic hemolytic anemia, and compensatory hematopoietic expansion are the d...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Hematology Am Soc Hematol Educ Program
Päätekijät: Cappellini, M. Domenica, Motta, Irene
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142569/
https://ncbi.nlm.nih.gov/pubmed/29222267
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