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Superiority and non-inferiority: two sides of the same coin?

BACKGROUND: The classification of phase 3 trials as superiority or non-inferiority has become routine, and it is widely accepted that there are important differences between the two types of trial in their design, analysis and interpretation. MAIN TEXT: There is a clear rationale for the superiority...

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Detalles Bibliográficos
Publicado en:Trials
Main Authors: Dunn, David T., Copas, Andrew J., Brocklehurst, Peter
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142414/
https://ncbi.nlm.nih.gov/pubmed/30223881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-2885-z
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