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Salivary‐gland‐protective regulatory T‐cell dysfunction underlies female‐specific sialadenitis in the non‐obese diabetic mouse model of Sjögren syndrome

Immune cell‐mediated destruction of salivary glands is a hallmark feature of Sjögren syndrome. Similar to the female predominance in humans, female non‐obese diabetic (NOD) mice develop spontaneous salivary gland autoimmunity. However, in both humans and mice it is unclear what factors contribute to...

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Vydáno v:Immunology
Hlavní autoři: Barr, Jennifer Y., Wang, Xiaofang, Kreiger, Portia A., Lieberman, Scott M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142283/
https://ncbi.nlm.nih.gov/pubmed/29750331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12948
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