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LARGE, an intellectual disability-associated protein, regulates AMPA-type glutamate receptor trafficking and memory
Mutations in the human LARGE gene result in severe intellectual disability and muscular dystrophy. How LARGE mutation leads to intellectual disability, however, is unclear. In our proteomic study, LARGE was found to be a component of the AMPA-type glutamate receptor (AMPA-R) protein complex, a main...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6142281/ https://ncbi.nlm.nih.gov/pubmed/29915039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805060115 |
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