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Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease

The limited host tropism of numerous viruses causing disease in humans remains incompletely understood. One example is Zika virus (ZIKV), an RNA virus that has reemerged in recent years. Here, we demonstrate that ZIKV efficiently infects fibroblasts from humans, great apes, New and Old World monkeys...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ding, Qiang, Gaska, Jenna M., Douam, Florian, Wei, Lei, Kim, David, Balev, Metodi, Heller, Brigitte, Ploss, Alexander
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142274/
https://ncbi.nlm.nih.gov/pubmed/29915078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803406115
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