Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections

Maternal Zika virus (ZIKV) infection during pregnancy is recognized as the cause of an epidemic of microcephaly and other neurological anomalies in human fetuses. It remains unclear how ZIKV accesses the highly vulnerable population of neural progenitors of the fetal central nervous system (CNS), an...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Muffat, Julien, Li, Yun, Omer, Attya, Durbin, Ann, Bosch, Irene, Bakiasi, Grisilda, Richards, Edward, Meyer, Aaron, Gehrke, Lee, Jaenisch, Rudolf
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142255/
https://ncbi.nlm.nih.gov/pubmed/29915057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719266115
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