Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice

Increasing prevalence in obesity has become a significant public concern. C57BL/6J mice are prone to diet-induced obesity (DIO) when fed high-fat diet (HFD), and develop chronic inflammation and metabolic syndrome, making them a good model to analyze mechanisms whereby obesity elicits pathologies. D...

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Publicado no:Front Immunol
Main Authors: Lainez, Nancy M., Jonak, Carrie R., Nair, Meera G., Ethell, Iryna M., Wilson, Emma H., Carson, Monica J., Coss, Djurdjica
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141693/
https://ncbi.nlm.nih.gov/pubmed/30254630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01992
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