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Structure, Function, and Modulation of γ-Aminobutyric Acid Transporter 1 (GAT1) in Neurological Disorders: A Pharmacoinformatic Prospective

γ-Aminobutyric acid (GABA) Transporters (GATs) belong to sodium and chloride dependent-transporter family and are widely expressed throughout the brain. Notably, GAT1 is accountable for sustaining 75% of the synaptic GABA concentration and entails its transport to the GABA(A) receptors to initiate t...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Zafar, Sadia, Jabeen, Ishrat
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141625/
https://ncbi.nlm.nih.gov/pubmed/30255012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00397
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