A modified HLA-A*0201-restricted CTL epitope from human oncoprotein (hPEBP4) induces more efficient antitumor responses

We previously identified human phosphatidylethanolamine-binding protein 4 (hPEBP4) as an antiapoptotic protein with increased expression levels in breast, ovarian and prostate cancer cells, but low expression levels in normal tissues, which makes hPEBP4 an attractive target for immunotherapy. Here,...

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Udgivet i:Cell Mol Immunol
Main Authors: Sun, Weihong, Shi, Junyi, Wu, Jian, Zhang, Junchu, Chen, Huabiao, Li, Yuanyuan, Liu, Shuxun, Wu, Yanfeng, Tian, Zhigang, Cao, Xuetao, Li, Nan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141579/
https://ncbi.nlm.nih.gov/pubmed/29375131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.155
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