Chronic kidney disease attenuates the plasma metabolome response to insulin

Chronic kidney disease (CKD) leads to decreased sensitivity to the metabolic effects of insulin, contributing to protein energy wasting and muscle atrophy. Targeted metabolomics profiling during hyperinsulinemic-euglycemic insulin clamp testing may help identify aberrant metabolic pathways contribut...

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Publicado en:JCI Insight
Main Authors: Roshanravan, Baback, Zelnick, Leila R., Djucovic, Daniel, Gu, Haiwei, Alvarez, Jessica A., Ziegler, Thomas R., Gamboa, Jorge L., Utzschneider, Kristina, Kestenbaum, Bryan, Himmelfarb, Jonathan, Kahn, Steven E., Raftery, Daniel, de Boer, Ian H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141172/
https://ncbi.nlm.nih.gov/pubmed/30135309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122219
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