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Renal tubule insulin receptor modestly promotes elevated blood pressure and markedly stimulates glucose reabsorption

Although the cause of hypertension among individuals with obesity and insulin resistance is unknown, increased plasma insulin, acting in the kidney to increase sodium reabsorption, has been proposed as a potential mechanism. Insulin may also stimulate glucose uptake, but the contributions of tubular...

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Publicado en:JCI Insight
Main Authors: Nizar, Jonathan M., Shepard, Blythe D., Vo, Vianna T., Bhalla, Vivek
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141164/
https://ncbi.nlm.nih.gov/pubmed/30135311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95107
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