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Variability of Genotype-specific Penetrance Probabilities in the Calculation of Risk Support Intervals

Previously, a maximum likelihood method was described to construct a support interval for the risk. This method is extended to incorporate genotype specific penetrance probabilities in the calculation of a risk support interval. As an empirical example, the support interval for the risk is calculate...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Leal, Suzanne M., Ott, Jurg
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141013/
https://ncbi.nlm.nih.gov/pubmed/8788022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.1370120655
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