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Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen

Candida albicans is a heterozygous diploid yeast that is a commensal of the human gastrointestinal tract and a prevalent opportunistic pathogen. Here, whole-genome sequencing was performed on multiple C. albicans isolates passaged both in vitro and in vivo to characterize the complete spectrum of mu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ene, Iuliana V., Farrer, Rhys A., Hirakawa, Matthew P., Agwamba, Kennedy, Cuomo, Christina A., Bennett, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140516/
https://ncbi.nlm.nih.gov/pubmed/30150418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806002115
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