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The importance of DNA methylation of exons on alternative splicing

Alternative splicing (AS) contributes to proteome diversity. As splicing occurs cotranscriptionally, epigenetic determinants such as DNA methylation likely play a part in regulation of AS. Previously, we have shown that DNA methylation marks exons and that a loss of DNA methylation alters splicing p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:RNA
Hauptverfasser: Shayevitch, Ronna, Askayo, Dan, Keydar, Ifat, Ast, Gil
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140467/
https://ncbi.nlm.nih.gov/pubmed/30002084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064865.117
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