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Adenine protonation enables cyclic-di-GMP binding to cyclic-GAMP sensing riboswitches
In certain structural or functional contexts, RNA structures can contain protonated nucleotides. However, a direct role for stably protonated nucleotides in ligand binding and ligand recognition has not yet been demonstrated unambiguously. Previous X-ray structures of c-GAMP binding riboswitch aptam...
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| Udgivet i: | RNA |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140456/ https://ncbi.nlm.nih.gov/pubmed/30006500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.067470.118 |
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