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Optimal Hydrophobicity and Reorientation of Amphiphilic Peptides Translocating through Membrane

Cell-penetrating and some antimicrobial peptides can translocate across lipid bilayers without disrupting the membrane structure. However, the molecular properties required for efficient translocation are not fully understood. We employed the Metropolis Monte Carlo method together with coarse-graine...

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Publicat a:Biophys J
Autors principals: Kabelka, Ivo, Vácha, Robert
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139821/
https://ncbi.nlm.nih.gov/pubmed/30177443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.08.012
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