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Neuropilin-2 regulates airway inflammatory responses to inhaled lipopolysaccharide

Neuropilins are multifunctional receptors that play important roles in immune regulation. Neuropilin-2 (NRP2) is expressed in the lungs, but whether it regulates airway immune responses is unknown. Here, we report that Nrp2 is weakly expressed by alveolar macrophages (AMs) in the steady state but is...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Immormino, Robert M., Lauzier, David C., Nakano, Hideki, Hernandez, Michelle L., Alexis, Neil E., Ghio, Andrew J., Tilley, Stephen L., Doerschuk, Claire M., Peden, David B., Cook, Donald N., Moran, Timothy P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139664/
https://ncbi.nlm.nih.gov/pubmed/29671604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00067.2018
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