The MST4–MOB4 complex disrupts the MST1–MOB1 complex in the Hippo–YAP pathway and plays a pro-oncogenic role in pancreatic cancer

The mammalian STE20-like protein kinase 1 (MST1)–MOB kinase activator 1 (MOB1) complex has been shown to suppress the oncogenic activity of Yes-associated protein (YAP) in the mammalian Hippo pathway, which is involved in the development of multiple tumors, including pancreatic cancer (PC). However,...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Chen, Min, Zhang, Hui, Shi, Zhubing, Li, Yehua, Zhang, Xiaoman, Gao, Ziyang, Zhou, Li, Ma, Jian, Xu, Qi, Guan, Jingmin, Cheng, Yunfeng, Jiao, Shi, Zhou, Zhaocai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Molecular Biophysics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139558/
https://ncbi.nlm.nih.gov/pubmed/30072378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003279
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