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A sulfur-free peptide mimic of surfactant protein B (B-YL) exhibits high in vitro and in vivo surface activities

Background: Animal-derived surfactants containing surfactant proteins B (SP-B) and C (SP-C) are used to treat respiratory distress syndrome (RDS) in preterm infants. SP-B (79 residues) plays a pivotal role in lung function and the design of synthetic lung surfactant. Super Mini-B (SMB), a 41-residue...

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Detalhes bibliográficos
Publicado no:Gates Open Res
Main Authors: Walther, Frans J., Gupta, Monik, Gordon, Larry M., Waring, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139377/
https://ncbi.nlm.nih.gov/pubmed/30234192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/gatesopenres.12799.2
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