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Neonatal Pain and Stress Disrupts Later-life Pavlovian Fear Conditioning and Sensory Function in Rats: Evidence for a Two-Hit Model
Early-life trauma has been linked to increased risks for anxiety, depression, and chronic pain. We used rodent models of acute and inflammatory neonatal pain to explore effects on fear conditioning and somatosensory function. Hindpaw needle pricks or handling on postnatal days (PNDs) 1–7 caused last...
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| Publicado no: | Dev Psychobiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6139181/ https://ncbi.nlm.nih.gov/pubmed/29749116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dev.21632 |
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