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Sequence-specific covalent capture coupled with high-contrast nanopore detection of a disease-derived nucleic acid sequence**

Hybridization-based methods for the detection of nucleic acid sequences are important in research and medicine. Short probes provide sequence specificity, but may not provide a durable signal. Sequence-specific covalent cross-link formation can anchor probes to target DNA and also may provide an add...

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Publicat a:Chembiochem
Autors principals: Nejad, Maryam Imani, Shi, Ruicheng, Zhang, Xinyue, Gu, Li-Qun, Gates, Kent S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139021/
https://ncbi.nlm.nih.gov/pubmed/28422400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700204
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