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Purinergic signalling in autoimmunity: A role for the P2X7R in systemic lupus erythematosus?

Purinergic signalling plays a crucial role in immunity and autoimmunity. Among purinergic receptors, the P2X7 receptor (P2X7R) has an undisputed role as it is expressed to high level by immune cells, triggers cytokine release and modulates immune cell differentiation. In this review, we focus on evi...

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Detalhes bibliográficos
Publicado no:Biomed J
Main Authors: Di Virgilio, Francesco, Giuliani, Anna Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Chang Gung University 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138817/
https://ncbi.nlm.nih.gov/pubmed/27884379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bj.2016.08.006
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