Focused ultrasound combined with microbubble-mediated intranasal delivery of gold nanoclusters to the brain

Focused ultrasound combined with microbubble-mediated intranasal delivery (FUSIN) is a new brain drug delivery technique. FUSIN utilizes the nasal route for direct nose-to-brain drug administration, thereby bypassing the blood-brain barrier (BBB) and minimizing systemic exposure. It also uses FUS-in...

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Veröffentlicht in:J Control Release
Hauptverfasser: Ye, Dezhuang, Zhang, Xiaohui, Yue, Yimei, Raliya, Ramesh, Biswas, Pratim, Taylor, Sara, Tai, Yuan-chuan, Rubin, Joshua B., Liu, Yongjian, Chen, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138562/
https://ncbi.nlm.nih.gov/pubmed/30009893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.07.020
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