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EMUDRA: Ensemble of Multiple Drug Repositioning Approaches to improve prediction accuracy

MOTIVATION: Availability of large-scale genomic, epigenetic and proteomic data in complex diseases makes it possible to objectively and comprehensively identify the therapeutic targets that can lead to new therapies. The Connectivity Map has been widely used to explore novel indications of existing...

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Vydáno v:Bioinformatics
Hlavní autoři: Zhou, Xianxiao, Wang, Minghui, Katsyv, Igor, Irie, Hanna, Zhang, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138000/
https://ncbi.nlm.nih.gov/pubmed/29688306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty325
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