An increased Bax/Bcl-2 ratio in circulating inflammatory cells predicts primary response to infliximab in inflammatory bowel disease patients

BACKGROUND: Predicting the response of inflammatory bowel disease (IBD) patients to infliximab (IFX) is an unmet clinical need. The expression and density of transmembrane tumor necrosis factor-α in circulating leukocytes maybe directly related to response by promoting apoptosis. AIM: We tested the...

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Detalhes bibliográficos
Publicado no:United European Gastroenterol J
Main Authors: Aghdaei, Hamid Asadzadeh, Kadijani, Azade Amini, Sorrentino, Dario, Mirzaei, Alireza, Shahrokh, Shabnam, Balaii, Hedieh, Geraci, Marco, Zali, Mohammad Reza
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137581/
https://ncbi.nlm.nih.gov/pubmed/30228896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640618774637
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