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Genetic ablation of androgen receptor signaling in fetal Leydig cell lineage affects Leydig cell functions in adult testis

It is commonly accepted that androgen-producing fetal Leydig cells (FLC) are substituted by adult Leydig cells (ALC) during perinatal testis development. The mechanisms influencing this process are unclear. We used mice with a retinoid acid receptor 2 promoter–Cre recombinase transgene (Rarb-cre) ex...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Kaftanovskaya, Elena M., Lopez, Carolina, Ferguson, Lydia, Myhr, Courtney, Agoulnik, Alexander I.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137449/
https://ncbi.nlm.nih.gov/pubmed/25713029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-263632
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