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Impaired Circadian Photoentrainment in Opn5-Null Mice

The master circadian pacemaker in mammals resides in the hypothalamic suprachiasmatic nuclei (SCN) and is synchronized to ambient light/dark cycles (i.e., photoentrainment). Melanopsin (Opn4) and classical rod-cone photoreceptors are believed to provide all the photic input necessary for circadian p...

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Bibliographic Details
Published in:iScience
Main Authors: Ota, Wataru, Nakane, Yusuke, Hattar, Samer, Yoshimura, Takashi
Format: Artigo
Language:Inglês
Published: Elsevier 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137434/
https://ncbi.nlm.nih.gov/pubmed/30240620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.08.010
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