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Coupling of DNA Replication and Negative Feedback Controls Gene Expression for Cell-Fate Decisions
Cellular decision-making arises from the expression of genes along a regulatory cascade, which leads to a choice between distinct phenotypic states. DNA dosage variations, often introduced by replication, can significantly affect gene expression to ultimately bias decision outcomes. The bacteriophag...
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| Veröffentlicht in: | iScience |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137276/ https://ncbi.nlm.nih.gov/pubmed/30240603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.07.006 |
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