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Mean-Independent Noise Control of Cell Fates via Intermediate States

Stochasticity affects accurate signal detection and robust generation of correct cell fates. Although many known regulatory mechanisms may reduce fluctuations in signals, most simultaneously influence their mean dynamics, leading to unfaithful cell fates. Through analysis and computation, we demonst...

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Detalhes bibliográficos
Publicado no:iScience
Principais autores: Rackauckas, Christopher, Schilling, Thomas, Nie, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137274/
https://ncbi.nlm.nih.gov/pubmed/30428314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.04.002
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